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MOCA Systems Inc. (MSI) has announced important enhancements to Touchplan, the leading digital production planning platform, enabling easy synchronization with Oracle’s project management and scheduling system, Primavera P6. The powerful union of technologies eliminates the problem of schedule drift, where the P6 master schedule in the back office becomes out of sync with live workflow events in the field, resulting in increased budget and schedule risks for large, complex construction projects.  P6, based on the Critical Path Method (CPM), is time oriented. It provides master planners with a broad, top-down project view, identifying the longest path of dependent activities (critical path) that determine the shortest possible project duration. The P6 contractual schedule is periodically updated to reflect the actual sequencing and duration of workflow tasks in the production plan.  Touchplan, based on the Last Planner System (LPS), is action oriented. It provides production managers and executives with a detailed, bottom-up project view, enabling worker collaboration, commitment,

Simulations Plus, Inc. (“Simulations Plus”), a leading provider of biosimulation, simulation-enabled performance and intelligence solutions, and medical communications to the biopharma industry, has released the latest version of its flagship quantitative systems toxicology (QST) platform, DILIsym® version X. “Modeling and predictions regarding drug efficacy are critical in the drug development process—but so are predictions regarding safety,” said Dr. Brett Howell , President of Quantitative Systems Pharmacology (QSP) Solutions at Simulations Plus. “We know there is often a gap between preclinical and clinical research toxicology results, but DILIsym is designed to help researchers identify potential DILI risks and, when appropriate, design dosing strategies that can mitigate or eliminate possible hazards. With the enhanced processing speed and improved user interface offered by DSX, clients get crucial insight into the safety of their drug candidate faster and more easily than ever before.” Branded as DSX™, the software is designed to support key drug development decisions by predicting potential drug-induced

Simulations Plus, Inc. (“Simulations Plus”), a leading provider of biosimulation, simulation-enabled performance and intelligence solutions, and medical communications to the biopharma industry, announced the release of version 12.0 of ADMET Predictor® (AP12), its flagship machine learning (ML) modeling platform for the discovery, design, and optimization of new molecules. AP12 includes: Enhanced Models : New and expanded models offer greater predictive accuracy, with an average 30% increase in training set sizes, for microsome and hepatocyte clearance, protein binding, biorelevant solubilities, MDCK-LE/PAMPA permeability, and more. High-Throughput Pharmacokinetics (HTPK) : New options for solution dosing, adjusted free fraction outputs, and species-specific simulations enhance the flexibility and precision of HTPK studies. Artificial Intelligence-Driven Drug Design (AIDD) : Integration of 3D shape matching and tissue sensitivities (based on tissue Kp values) as new objectives, facilitating innovative lead optimization processes. New DILI Module : Introduction of the first drug-induced liver injury (DILI) endpoint models to support high-throughput (HT) DILIsym® predictions in early drug development. Boosted ANN Regression Models and added

TECHNIA, the #1 knowledge leader in virtual twin solutions and digital engineering, today announced the release of myPLM 2.0. This latest version introduces significant improvements and innovative features designed to make the management and use of CAx environments more efficient and user-friendly. myPLM accelerates the use of complex CAx environments such as CATIA V5, 3DEXPERIENCE, NX, and Creo, and enables the management of various customer-specific CAx versions, licenses, and additional products. "myPLM 2.0 has taken a big step forward. The new user interface and the improved functions are very well received by users. The license traffic light and the notification system are particularly advantageous" Jan Heger, myPLM Product Manager. Product Highlights of myPLM 2.0: New User Interface (UI) and Modern User Experience (UX): The updated UI features a fresh, modern design, making the software easier to navigate and use. 4K/8K Support: myPLM 2.0 is fully compatible with high-resolution 4K and 8K displays, offering improved visual clarity and detail. Dark Theme: Users can now